Scientists have found a substance in red wine that is slowing down the aging process in mice. Will it someday lengthen the lives of humans, too? Morley Safer reports. … CBS News 60 Minutes Morley Safer Wine Resveratrol
Let us outline here the Resveratrol benefits. Reveratsol is a powerful nutrient found primarily in grapes. Also found in peanuts and blueberries, this nutrient is gaining significant acclaim for its unique ability to improve longevity in many types of animals. Researchers are hoping to better understand the many benefits that resveratrol may hold. Along with grapes, blueberries and peanuts, resveratrol is present in wine, particularly red wine, which has been presented as potentially beneficial. That being said, red wine only has 100 mcg, or 0.1 mg, of resveratrol per glass. The nutrient is also be found in grape juice. Individuals who want to get resveratrol benefits for support for diabetes, heart disease or general health, should consider supplementing 20 mg daily. Various data collected suggested 20 mg is enough to supply benefits for the body.
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Some of the greatest interest in resveratrol right now concerns its link to enhancing longevity. Medical research has consistently demonstrated that significant calorie restriction can lead to a longer life span. In fact, it is the only proven way to substantially improve the length of life. Resveratrol was found to stimulate certain pathway triggers called sirtuins, which are the same messengers activated during calorie restriction The problem with calorie restriction is that it is very difficult to accomplish without putting a major interference in one’s quality of life. Resveratrol could offer hope to improve longevity without having to feel hungry all of the time. This is particularly important for diabetics who tend to have shorter life spans due to related problems like heart disease, cancer and damage to nerves that follow the insulin resistance.
Resveratrol benefits just might help protect against many of these chronic problems, including the main trouble of insulin resistance. By improving blood sugars and increasing the longevity of the cells of the body, resveratrol may help diabetics obtain an overall improvement in morbidity and mortality. There are several other benefits from this natural nutrient. It appears that resveratrol might actually work in several ways to help the body prevent cancer. Resveratrol could also benefit men’s general health and women with a previous history of breast cancer by blocking the over conversion of testosterone to estrogen. It could also help the body by blocking the effects of carcinogens and hastening their removal.
Resveratrol benefits to the blood vessels are many. It can protect the body from further damage after a heart attack or stroke. Its antioxidant properties can help the heart during times of decreased blood flow. Inflammation, which can play a role in heart disease, as well
as cancer and various diseases of the brain, is improved with resveratrol. The heart might be helped even more by resveratrol’s ability to make the platelets less sticky and prevent damage from cholesterol. By calming inflammation, resveratrol might also help prevent damage to the brain, including diseases like Alzheimer’s, and protect neurons from toxicity. In addition to all of this, resveratrol may even help fight the swine flu, as it has been shown to decrease replication of the flu virus in many studies.
We are well aware of the desire in medical and nutritional ventures to find the magic bullet that will stop aging. And while we are very excited to share these resveratrol benefits, we should be aware that health and aging are multi-factorial and no single elixir exists. Let us have some words about increasing resveratrol and polyphenol intake via diet and supplements. Polyphenols are richest in fruits in general. The berries are the generally richest source of anthocyanins subgroup of polyphenols. Red wine polyphenol concentration depends on many factors, such as type, climate and soil. Even the best red wines may have little more than 2 mg per liter. But research suggests that at least ten times that amount (20 mg) is needed to begin to optimize the health benefits potential in resveratrol and a hundred times that or more (100 to 200 mg +) for actual potential therapeutic purposes. Because resveratrol is highest in Polygonum Cuspidatum, combining this single phytonutrient in pharmaceutical grade with red wine whole grape polyphenols (RWP), as naturally found in nature, is likely the best supplemental approach. Quercitin, another polyphenol especially abundant in green apple skins and onions, enhances viability. As with most supplements, there is a great deal of variability in quality, quantity, and activity. Unfortunately, as Consumer Report type exposes continually inform us, it is hard to tell what is in a bottle just be reading the label.
The wonder Resveratrol can be packaged and purchased in bulk. Price break examples can be as follows:
- 1 - 5 Kilograms
- 6 - 10 Kilograms
- 11 - 25 Kilograms
- 26+ Kilograms and prices vary depending on order size, availability and shipping distance.
They can also come in advanced nitrogen gas filled liquid capsules, micronized for better absorption. Micronized Resveratrol with tween offer some of the highest absorption of Resveratrol in bulk currently on the market and can also offer the highest concentration of resveratrol in a capsule. The resveratrol absorption in this technology is estimated to be 5x or more than ordinary non-micronized resveratrol capsules.
If you opt for pure synthetic Resveratrol in bulk, it has the advantage that it is completely free from plant contaminants which may have negative effects, while being exactly the same chemical as occurs in nature in red wine, among other sources. In order to obtain a supply of Resveratrol in bulk for yourself, you can look for other interested parties to join you in a large bulk purchase, so that together you may get the far lower price per gram that the supplier will give for a large order. 
All Resveratrol in bulk purchases can be packaged in 50 or 100 gm amounts in polypropylene (PP) zip-lock bags with all air expelled before the bag is closed. PP bags are much more moisture and air proof than are polyethylene (PE) bags, which is the standard that one gets at the supermarket. Each PP bag is placed in a zip-lock PE sandwich bag for added protection. Multiple bags are then placed into a bubble envelope which is then placed inside a flat rate priority mail envelope for shipments of 200 grams or less and a priority box for more than that. For those outside the US things may be done a little differently as appropriate to a country’s Customs requirements.
On storage and handling, if the Resveratrol in bulk bags are kept in a freezer and inside a light proof container, there will be little degradation over a period of 2 years. Researchers stated nothing about storage in nitrogen during the experiment and most of the storage time was in a refrigerator mixed with chow. During actual usage everyone would be wise to expel all air from the bag whenever it is re-closed after getting some out of it. When you remove some Resveratrol in bulk from a larger package, only remove enough to last for, say, ten days or 2 weeks at a time and, when not in use, keep it in a small PP ziplock bag in a dark bottle in the refrigerator. Small PP zip-lock bags will be enclosed with every shipment package for the purpose of keeping this smaller in-use amount in the refrigerator.
On Resveratrol in bulk shipping and payment, all prices may include priority mail (USPS) shipping to US addresses and a copy of the Certificate of Analysis (COA) of the product. Be prepared to pay in advance by check or money order as soon as there are sufficient number of participants to place a large order (25 kg) which is likely within a month, since this is a joint bulk purchase and must be fully prepaid.
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